TABLE 3.

Frequency of detection in gut and liver of RRV and SA11-Cl4 reassortants following oral inoculation of neonatal mice

Virus (n)a% RecoveryParental origin of genome segmentsd (gene product)
GutbLiverc1 (VP1)2 (VP2)3 (VP3)4 (VP4)5 (NSP1)6 (VP6)7 (NSP3)8 (NSP2)9 (VP7)10 (NSP4)11 (NSP5)
RRV (110)9226RRRRRRRRRRR
SA11-Cl4 (67)271SSSSSSSSSSS
S4,5 (35)10042RRRSSRRRRRR
S10 (36)9827RRRRRRRRRSR
R5,7 (69)7817SSSSRSRSSSS
S11 (28)5411RRRRRRRRRRS
R7 (35)899SSSSSSRSSSS
S3,5 (31)849RRSRSRRRRRR
S5 (98)936RRRRSRRRRRR
R5 (55)454SSSSRSSSSSS
S7 (30)773RRRRRRSRRRR
R10 (36)252SSSSSSSSSRS
R11 (32)280SSSSSSSSSSR
S5,7 (35)260RRRRSRSRRRR
R4 (30)230SSSRSSSSSSS
R9 (44)230SSSSSSSSRSS
R4,6,9 (27)160SSSRSRSSRSS
R3 (35)110SSRSSSSSSSS
  • a n, number of individual pups inoculated with each virus.

  • b Percentage of animals in which virus was recovered from the intestine 3 and 5 days postinoculation.

  • c Percentage of animals in which virus was recovered from the liver 3 and 5 days postinoculation.

  • d RRV-derived genome segment numbers converted to SA11 functional equivalent. R, segment derived from RRV; S, segment derived from SA11-C14.