TABLE 1.

Role of HRV in lung diseasesa

Clinical syndromePopulation cohort% virus-infected subjects% HRV-infected subjectsbReferences
SickWellSickWell
Acute illness
    BronchiolitisOutpatient with wheezing aged <2 years66-6825-3133-4511-2621, 58, 66
Hospitalized or emergency department patient aged <2 years86-9310-307, 42, 72
    PneumoniaHospitalized childrenc55-6524-4548, 61, 112
Immunocompromised adultsc17-194-820, 39
Exacerbation of chronic lung disease
    AsthmaOutpatient children62-8112-4152-5412-2844, 47
Hospitalized children61-6318-2348-572-1933, 51
Outpatient adults44-763-1318-480-132, 32, 52, 85
Hospitalized adults26-481810-35429, 108
    COPDOlder adults22-6412-193-360-454, 77, 96, 100, 108
    Cystic fibrosisChildren2816105
  • a Studies in the table are limited to those using molecular techniques for detection of HRV. Some of the studies mentioned in the article used diagnostic techniques that did not differentiate between HRV and enteroviruses and reported detection rates for picornaviruses. Some studies did not include control data for virus detection in well children.

  • b Data for infections with HRV as a single viral pathogen.

  • c Bacterial and viral pathogens codetected in some infections.