TABLE 2.

Expression of OCLN splicing forms in human liver samples

OCLN splicing formExpression assayIntersample variation (fold) when normalized tod:
B2M expressionaB2M and WT-OCLN expressionb
WT-OCLNExons 3 and 418
OCLN-ex4delExons 3 to 5165
OCLN-ex7extExon 7 extension9047
OCLN-ex3pdelPartial exon 3 and exon 419113
OCLN-ex3delExons 2 to 42216
OCLN-ex3-4delExons 2 to 5c306367
OCLN-ex3p-9pdelExons 3 to 9NDND
OCLN-ex3p-7pdelExons 3 to 7NDND
  • a Intersample variation when normalized to expression of the endogenous control B2M.

  • b Intersample variation when normalized to expression of endogenous control B2M and then to expression of WT-OCLN in each sample.

  • c The signal is also detected in DNA—might detect the OCLN pseudogene.

  • d ND, expression of mRNA transcripts is not detected with this assay in any of the samples.