TABLE 2.

Multiplicity of HIV-1 infection in IDU, heterosexual, and MSM subjects

CohortReferenceVirus subtypeTotal no. of subjectsSingle-variant transmissionMultiple-variant transmissionP valueOdds ratio95% CIMedianRange
No. of subjects% of totalNo. of subjects% of total
HeterosexualsKeele et al. (18)B796582.301417.7011-4
Abrahams et al. (1)C695478.301521.7011-5
Haaland et al. (13)A or C272281.50518.5011-6
Total17514180.603419.400.008a6.141.37-31.2711-6
MSMKeele et al. (18)B221359.10940.9011-6
Li et al. (24)B281864.301035.7011-10
Total503162.001938.000.294b2.410.50-13.2011-10
IDUsBarB10440.00660.0031-16
  • a Fisher's exact test of multiple-variant transmission in heterosexuals versus in IDUs.

  • b Fisher's exact test of multiple-variant transmission in MSM versus in IDUs.