TABLE 2.

Number and percent distribution of anti-gp41 antibodies

Patient no.No. of unique B-cell clones (%)No. of clonal members (%)No. of clones (%) by cluster(s)
IIIIVII, IVI, IVVI, II
17221200
161121200
29421200
422296500
314035600
3701811800
414421241
297222142
51100000
3300000
62011000
4031000
Total B-cell clones (single cluster)a47 (100)11 (23)10 (21)9 (19)12 (26)4 (9)1 (2)
Total B-cell clones (two clusters)a(134)15 (32)23 (49)25 (53)
Total clonal members (single cluster)131 (100)43 (33)34 (26)21 (16)17 (13)14 (11)2 (2)
Total clonal members (two clusters)(124)57 (44)53 (40)52 (40)
  • a Totals reported refer to the sum of the individual clones or clonal members binding their cluster(s). Totals for a single cluster indicate the binding of the antibodies as mapped; totals for two clusters distribute the antibodies that bound to two clusters evenly to their single clusters.