TABLE 1.

Sample summarya

SubjectSexAge (mos)Additional diagnosisOutcomeNo. of subclones analyzed by Sanger sequencingNo. of sequences obtained by 454 pyrosequencingEukaryotic virus(es) detected
AFP patients
    1449M96UnknownResidual weakness4914,713Cosavirus, nodavirus-like virus
    6278F30HemiplegiaResidual weakness1308,924None
    6341M4HemiplegiaFull recovery575,456None
    6344M60UnknownFull recovery10223,477Cosavirus, dicistrovirus-like virus
    5727F24OtherResidual weakness1303,715Tobacco green mosaic virus
    6178M36HemiplegiaDeath18120,052Cosavirus, dicistrovirus-like virus, anellovirus (TTV), HEV-B, HEV-C
    6187M60Encephalitis/meningitisFull recovery24017,705Aichi virus, adenovirus
    5192M36UnknownFull recovery594,019Adenovirus, Aichi virus, cosavirus
    5550M1NPE myelitisDeath528,276Adenovirus, cosavirus, HEV-B, HEV-C, cucumber mosaic virus, rhinovirus
    6572F48UnknownUnknown12925,516Cosavirus, HEV-C, HEV-B, human cardiovirus, plant virus
    1988M13OtherFull recovery45HEV-B
    2111F120HypokemiaFull recovery40HEV-A
    2131M11HypokemiaFull recovery36HEV-A, HEV-B
    2178M30UnknownResidual weakness50Adenovirus, HEV-C
    2204M15UnknownResidual weakness45HEV-A
    2255F12HypokemiaFull recovery38Parechovirus, picobirnavirus, pepper mottle virus
    2263F24HemiplegiaResidual weakness47Aichi virus, tobacco green mosaic virus
    2291M122OtherFull recovery41Aichi virus
    2295F26Traumatic neuritisFull recovery39Aichi virus, picobirnavirus
    2296M174UnknownDeath92Cosavirus, HEV-B
    2299M96HemiplegiaResidual weakness40HEV-A
    5002F7HypokemiaFull recovery58Rotavirus
    5003M7Traumatic neuritisFull recovery91Anellovirus (TTV), HEV-B, human cardiovirus, rotavirus
    5004M72UnknownResidual weakness43HEV-A
    5005M96OtherFull recovery44HEV-A
    5008M36UnknownFull recovery35HEV-A
    5034M84UnknownResidual weakness110Cosavirus, HEV-C
    5048M42UnknownUnknown62None
    5152M156OtherFull recovery41Human cardiovirus, unclassified Partitiviridae viruses
    5222F60UnknownUnknown88None
    5510M36UnknownFull recovery98Bocavirus, dicistrovirus-like virus, HEV-C
    5551M8Encephalitis/meningitisResidual weakness133Rotavirus
    6197F23Encephalitis/meningitisDeath183HEV-B, HEV-C
    6377M84Traumatic neuritisFull recovery44None
    6584F72UnknownUnknown85None
Contacts
    5006CF24NANA83Aichi virus, cosavirus, circovirus-like virus, HEV-C
    5045CM25NANA86HEV-C, parechovirus
    5044CF24NANA70HEV-C, anellovirus (TTV)
    5046CF6NANA91Cosavirus, HEV-B, HEV-C, rhinovirus, anellovirus (TTV)
    5047CM11NANA47HEV-B, HEV-C
    5048CM48NANA62Cosavirus, HEV-A, HEV-B, HEV-C
  • a M, male; F, female; NA, not applicable; NPE, nonpolio enterovirus.