TABLE 2.

Virus loads, slopes of CD4 T-cell decline, and potential CTL escape mutations in patients in this study

Patient IDViral load at entry (copies/ml)Viral load at set point (copies/ml)aCD4 slope (cells/μl)No. of CTL epitopes in first available sampleb
Mutant CTL epitopesSensitive CTL epitopes
PRRTPRRT
30213,78263,265−0.1618d11
3024115,721173,550−0.31c3d8d04
303640,91261,459−0.814d5d314
303747,27282,106−0.28c57NANA
3041143,50521,248−0.0714d36
306234,29919,476−0.08c2d3d17
3077187,982722,9260.33d4d412
30881,392,011470,189−0.5527NANA
1001300,815136,647−0.46c5d10d12
1002671,67917,317−1.2124NANA
1003110,000,000453,737e−0.89c48NANA
10049,347,80067,989−0.2618NANA
1005750,00052,148−0.11c24NANA
1006500,00022,8760.4636NANA
  • a Mean viral load at 3 months postseronconversion.

  • b Values in bold indicate that the HLA type is known. NA, not available.

  • c CD4 count declined to <200 during the observation period.

  • d Mutant CTL epitopes matched patient HLA type.

  • e Only a single sample was available at 3 months postseroconversion.