TABLE 2.

Summary of cytotoxic T-lymphocyte epitopes derived from CMV pp65

Peptide group and nameaAmino acid sequencePositionReference(s)
Newly identified epitopes and HLA class I restriction elements
    B57 VF9VAFTSHEHF294-302
    C6 TI9TRATKMQVI211-219
Previously reported epitopes and HLA class I restriction elements
    A1 YY11YSEHPTFTSQY363-37344, 57
    A2 NV9NLVPMVATV495-50311, 72
    B35 IY9IPSINVHHY123-13117
    B40 HL9HERNGFTVL267-27535
    B44 EY10EFFWDANDIY512-52171, 72
    B44 SY10SEHPTFTSQY364-37313, 35
    B52 QV9QMWQARLTV155-16331
15-mer peptides recognized in peptide matrix mapping experiments
    15PCHRGDNQLQVQHTY67-81
    33HRHLPVADAVIHASG139-153
    44TSAFVFPTKDVALRH183-197
    49ELVCSMENTRATKMQ203-217
    54YVKVYLESFCEDVPS223-237
    56FCEDVPSGKLFMHVT231-245
    64FMRPHERNGFTVLCP263-277
    94HTWDRHDEGAAQGDD383-397
    109ATACTAGVMTRGRLK443-457
  • a Abbreviated as HLA class I restriction element followed by CMV peptide sequence identified as first and last amino acid symbols followed by sequence length.