TABLE 4.

Comparison of circulating immune complexes with WHs antigenemia, WHV viremia, and anti-WHc response in woodchucks with established chronic WHV infection

WoodchuckaCIC (signal strength)bWHsAg (ODU)WHV DNA (WHVge/ml)Anti-WHc (ODU)
M6539+++0.3197.5 × 10100.295
F5954++0.2286.7 × 10100.122
M6510++0.1772.6 × 10100.195
F5904+0.2187.7 × 1090.226
F5927+0.1839.2 × 1090.152
M59510.2054.0 × 10100.122
F58830.1961.8 × 10100.077
F58900.1727.6 × 1090.097
F59290.1547.2 × 1090.131
  • a Woodchucks were infected experimentally as neonates at 3 days of age with 5 × 106 WID50 of the WHV7P1 inoculum.

  • b +++, high; ++, intermediate; +, low; −, no signal.