TABLE 2.

Comparison of genomic features and amino acid identities between BuCoV HKU11, ThCoV HKU12, and MuCoV HKU13 and other CoVsa

CoVGenome featuresPairwise amino acid identity (%)
Size (bases)G+C contentBuCoV HKU11ThCoV HKU12MuCoV HKU13
3CLproPolHelSN3CLproPolHelSN3CLproPolHelSN
Group 1a
    PEDV280330.4236.749.147.835.521.335.848.848.135.821.636.449.647.937.422.4
    TGEV285860.3833.449.550.933.523.533.149.550.734.522.534.149.850.134.023.1
    FIPV293550.3834.949.650.634.523.735.349.350.434.822.434.750.449.834.222.9
Group 1b
    HCoV-229E273170.3833.848.849.741.419.034.248.848.840.821.434.549.649.740.520.3
    HCoV-NL63275530.3435.649.049.536.521.234.649.249.336.022.335.749.649.336.921.6
    Bat-CoV HKU2271650.3935.150.150.323.821.934.449.950.625.920.833.450.150.224.121.6
    BtCoV 1A283260.3833.849.251.534.221.834.248.651.033.623.934.149.551.134.423.6
    BtCoV 1B284760.3932.848.750.533.223.233.948.451.233.723.834.149.250.734.124.1
    Bat-CoV HKU8287730.4232.849.449.134.421.433.149.348.835.019.232.849.649.134.920.9
Group 2a
    HCoV-OC43307380.3738.151.348.320.922.038.151.347.823.919.237.552.149.324.821.0
    BCoV310280.3738.551.448.424.821.738.451.347.922.619.437.852.349.425.420.8
    PHEV304800.3738.551.448.325.521.938.451.347.824.320.737.852.149.325.219.6
    AntelopeCoV309950.3738.551.548.425.021.738.451.447.925.619.437.852.449.425.720.8
    GiCoV309790.3738.551.548.425.121.738.451.447.925.619.437.852.449.425.820.8
    MHV313570.4237.051.547.625.523.738.351.347.525.222.836.252.849.124.924.2
    HCoV-HKU1299260.3236.551.447.925.223.838.250.947.824.423.035.652.149.324.323.6
Group 2b
    SARS-CoV297510.4135.151.451.525.823.735.151.050.526.623.435.151.251.926.323.6
    Bat-SARS-CoV HKU3297280.4135.151.451.627.023.232.951.350.725.522.834.850.951.925.523.0
Group 2c
    Bat-CoV HKU4302860.3833.651.350.825.224.733.351.249.725.422.935.050.650.023.925.1
    Bat-CoV HKU5304880.4333.650.350.825.823.032.650.349.525.623.635.050.350.022.924.4
Group 2d
    Bat-CoV HKU9291140.4135.152.651.226.123.235.852.550.425.723.135.151.551.426.422.8
Group 3a
    IBV276080.3843.654.256.427.030.243.854.456.628.729.043.554.756.128.230.4
    TCoV276570.3843.354.057.428.630.244.154.757.530.030.043.154.656.829.729.6
Group 3b
    SW1316860.3940.352.352.826.231.439.052.852.824.730.637.152.552.825.930.1
Group 3c
    BuCoV HKU11264760.3988.392.596.746.374.679.888.493.668.172.5
    ThCoV HKU12263960.3888.392.596.746.374.680.586.993.148.175.4
    MuCoV HKU13265520.4379.888.493.668.172.580.586.993.148.175.4
  • a Comparison of genomic features of BuCoV HKU11, ThCoV HKU12, and MuCoV HKU13 and other CoVs with complete genome sequences available and of amino acid identities between the predicted 3CLpro, RNA-dependent RNA Pol, helicase (Hel), S, and N proteins of BuCoV HKU11, ThCoV HKU12, and MuCoV HKU13 and the corresponding proteins of other CoVs. PEDV, porcine epidemic diarrhea virus; TGEV, porcine transmissible gastroenteritis virus; FIPV, feline infectious peritonitis virus; BtCoV 1A, bat CoV 1A; BtCoV 1B, bat CoV 1B; BCoV, bovine CoV; AntelopeCoV, sable antelope CoV; GiCoV, giraffe CoV; PHEV, porcine hemagglutinating encephalomyelitis virus.