TABLE 1.

Determination of prion titers in wild-type and CXCR3−/− brain tissue in recipient tga20 mice

Donor genotypeTime after inoculation of donor (dpi)Survival of recipient tga20 mice (dpi)Titer (LD50/ml of 10% brain homogenate)
Wild type1251179.0 ± 103
Wild typeTerminal854.2 ± 105
CXCR3−/−125892.1 ± 105
CXCR3−/−Terminal835.8 ± 105