TABLE 1.

Amino acid polymorphisms in the Mx proteins from the CEF lines used in this studya

LineAmino acid in Mx protein at position:
52141428594185199202232308339548583631
A1RRPLLRKGSGVTATS
A2RQPLLRKGTGIAATS
8.1RRPLLRKGSGVTVTS
B1RRPLLRKGSGVTATN
C1RRPLLRKGSRVTVTN
D1RQRSLRKGSGVTVTN
DF-1RQRSLRKGSGVTVTN
SHKbRQRSLRKSTGVTVTN
WLRcWQRSLQKGSGIAAAS
Anti-VSV active linebWLK-2WLK-2WLK-2WLK-2WLK-2HNHN
  • a The amino acid residues at the 15 reported polymorphic sites of the chicken Mx protein are given for the CEF and DF-1 cell lines, with reference to those of the Shamo (SHK) and White Leghorn (WLR) lines. Bold type indicates where the amino acid is the same as that found in SHK. The bottom row shows breed identifiers, as given in reference 14, for Mx alleles that differ from the SHK amino acid at the positions shown but which are active against VSV. (The allele WLK-2 is from a strain of White Leghorn, and the HN allele is from the Hinaidori breed.)

  • b Data from reference 14.

  • c Accession number Z23168.