Study design showing the doses of DNA used for priming and the routes of immunization

GroupaNo. of volunteersDNAb dose (mg)Route of DNA immunization
A111.2i.d. at 4 sites
B111.2i.m. at 2 sites
C67.2i.m. at 2 sites
  • a Each group received 5-valent gp120 in either a single boost of 0.375 mg (group C) or two boosts of 0.375 mg each (groups A and B).

  • b The DNA vaccine contained DNA for 5-valent gp120 (from subtypes A, B, C, E, and Bal) and a single Gag protein (from subtype C).