TABLE 1.

Amino acid mutations identified in six CVB3 clones following selection for TBZE-029-resistant variants

CVB3 proteinAmino acid substitutionNucleotideClone(s)
SubstitutionPosition
2CK107RAAG→AGG36202
2CA224V/LGCA→GTA/TTA3971/39701, 2, 3, 4, 6/5
2CI227VATT→GTT39791, 2, 3, 4, 5, 6
2CA229VGCT→GTT39861, 2, 3, 4, 5, 6
3DS299TTCA→ACA60646