TABLE 1.

JCV genotypes detected in various populations

GenotypeaMajor domain in the eastern hemispherebIncidence (%) of genotypec in:
Southern CaliforniansSecond-generation Japanese-AmericansThird-generation Japanese-Americans
EU (types 1 and 4)Europe, Mediterranean areas17/33 (52)e 1/35 (3)0/18 (0)
Af2 (type 3)Africa, West Asia0/33 (0)1/35 (3)1/18 (6)
B1-c (type 2B)Europe1/33 (3)0/35 (0)0/18 (0)
B1-dSaudi Arabia, Greece1/33 (3)0/35 (0)0/18 (0)
CY (type 7B)Japan, South Korea, North China, Mongolia2/33 (6)25/35 (71)f 12/18 (67)f
MY (type 2A)Japan, South Korea6/33 (18)8/35 (23)4/18 (22)
SC (type 7A)Southeast Asia, South China, Pacific Islands4/33 (12)0/35 (0)0/18 (0)
OtherNDd 2/33 (6)0/35 (0)1/18 (6)
  • a Genotypes designated by Guo et al. (13) and Sugimoto et al. (34) and those (in parentheses) designated by Agostini et al. (6) are indicated.

  • b References 13, 31, and 34.

  • c Identified according to a phylogenetic tree (not shown) constructed from IG sequences.

  • d ND, not detected in the eastern hemisphere.

  • e Significantly different from values obtained with second- and third-generation Japanese-Americans (P < 0.01).

  • f Significantly different from value obtained with Southern Californians (P < 0.01).