TABLE 1.

Experimental design of passive immunization studies on mice

ExptAmt of MAb (μg)MAb(s)Day(s) of vaccinationChallenge virus(es)Age of mice
125D2.2, S109.8, S227.14, S230.15−1icUrbani, icGZ02, icHC/SZ/61/0312 mo
2250D2.2, S109.8, S227.14, S230.15−1icUrbani, icGZ02, icHC/SZ/61/0312 mo
3250S109.8 + S227.14 + S230.15 (cocktail)−1icHC/SZ/61/0312 mo
4250S230.15−1icHC/SZ/61/0310 wk
525D2.2, S109.8, S227.14, S230.15−1icMA1510 wk
6250S230.15−1, 0, 1, 2, 3GZ0212 mo