TABLE 1.

Effect of overexpression of PML on the replication of wild-type and Δα0 mutant viruses

VirusCell lineBaculovirusVirus yield (PFU) at indicated hours after infection
224
HSV-1(F)pHFWTa1.92 × 1042.5 × 107
Bac-PML2.63 × 1041.3 × 107
HEp-2WT3.5 × 1057 × 108
Bac-PML4 × 1055.5 × 108
R7910pHFWT1.47 × 1056.8 × 106
Bac-PML1.48 × 1057 × 106
HEp-2WT1.35 × 1051.5 × 107
Bac-PML1.1 × 1059 × 106
  • a WT, wild type.