TABLE 1.

Reactivities of human MAbs with V3JR-CSF-FP and V3JR-CSF linear peptides

MAbHalf-maximal binding toa:P value
V3-FPV3 peptide
21820.02 ± 0.010.14 ± 0.030.071
21910.04 ± 0.020.83 ± 0.090.015
22190.02 ± 0.010.84 ± 0.160.036
24120.02 ± 0.012.21 ± 0.010.0001
24420.02 ± 0.011.40 ± 0.20.02
24560.03 ± 0.022.10 ± 0.40.035
447-52Db0.01 ± 0.010.16 ± 0.070.17
  • a ELISA plates coated with V3-FP and V3 peptide at 59 nM concentration; mean of two experiments (micrograms per milliliter ± standard deviation).

  • b Control human anti-V3 MAb selected with V3MN peptide.