TABLE 2.

Effect of proline substitutions at residues near position 559

ResidueExpressionaTrimer stabilitybCleavagec
L555d ND
L556++±
R557++±
A558++±
I559d ++++++
E560+++±
A561+++±
Q562+++±
Q563+++±
R564+++±
M565++±
L566d ±±
  • a See Table 1, footnote a.

  • b See Table 1, footnote b.

  • c See Table 1, footnote c.

  • d Also shown in Table 1.