TABLE 1.

Induction of ISGs in Huh7 cells by IFN-α and in HCV-infected human and chimpanzee livers

ISGGenBank accession no.Reference(s) reporting induction by:Effect on HCV in 293 cellsa
IFN-α in Huh7 cellsHCV-infected livers
ISG5600154832, 39, 45, 49, 535, 6, 33, 39, 58, 61
GBP100205332, 39, 456, 35, 58
ISG9-2700364132, 45, 49, 536, 35, 61
1-8D006435536
1-8U02103453
MTAP44D2891532, 535, 6, 33
ADAR10011116, 35, 39
ISG2000220139, 456, 39+
ViperinAF44215133, 39, 496, 33, 61+
PKRAH00842932, 45, 53+
ISG1500510132, 39, 455, 6, 33, 39, 58, 61
OAS101681632, 39, 455, 6, 33, 39, 61
OAS100253432, 39, 45, 535, 6, 39, 61
OAS-L00373332, 39, 456, 35, 61
OAS-L19821332, 39, 456, 35, 61
PLSCR102110539, 45, 536, 39
MAPK800275032
SAMHD10154743233, 39
IFI4400641739, 45, 496, 61
IFI44L0068203939
UBE2L600422332, 456, 39, 61
USP1801741432, 39, 456, 39
BST200433545, 5335
FLJ20637AK000644536, 61
FLJ38348AK095667536
STAF50X8220039, 455, 6, 33, 39, 58
ISG12BN000227396, 39
FLJ20035AK000042456
C1ORF9DQ05338145
  • a + indicates the ISG inhibits the replication of HCV replicons.