Inoculum (no. of calves) | Mean no. of days of virus shedding (range) | Diarrhea^{b} | No. of calves positive/total no. of calves (%) | ||||
---|---|---|---|---|---|---|---|

No. of calves positive/total no. of calves (%) | Mean no. of days (range) | Mean cumulative score^{c} (range) | Viremia^{d} | Seroconversion^{e} | Coproconversion^{e} | ||

HS66 (n = 5) | 3 (1-6) | 5/5 (100) | 3 (2-6) | 10 (2-14) | 1/5 (20) | 2/3 (67) | 3/3 (100) |

Control (n = 4) | 0 | 1/5 (20) | 0 | 2 (1-4) | 0/5 (0) | 0/2 (0) | 0/2 (0) |

↵

*a*Due to the small number of animals used in the study, statistical significance was omitted.↵

*b*Diarrhea was deemed to be present if fecal swab scores were ≥2 after inoculation.↵

*c*Represents the sum of daily rectal swab scores from PIDs 1 to 6 of each calf divided by the number of calves in that group.↵

*d*Viremia was determined by RT-PCR on PID 2.↵

*e*Seroconversion and Ab titers in IC were determined by immunocytochemistry (HS66 recombinant baculovirus-infected Sf9 cell staining assay) at PIDs 21 and/or 28.