TABLE 1.

Progeny characteristics of complemented WT and deletion genomes in this study

Inserted ORF coding for:Deletion genomeWT genome
BACProgenyaBACProgenya
N-M50ΔM50/N-M50+++NDbNA
C-M53ΔM53/C-M53+++NDbNA
UL50ΔM50/UL50+++NDbNA
UL34(HSV-1)ΔM50/UL34(HSV-1)WT/UL34(HSV-1)+++
UL34(PrV)ΔM50/UL34(PrV)WT/UL34(PrV)+++
UL53ΔM53/UL53+++NDbNA
UL31(HSV-1)ΔM53/UL31(HSV-1)WT/UL31(HSV-1)+++
UL31(PrV)ΔM53/UL31(PrV)WT/UL31(PrV)+++
Orf69ΔM53/Orf69WT/Orf69+++
MPΔM53/MPWT/MP
MGΔM53/MGWT/MG+
  • a +++, reconstituted as WT; +, delayed reconstitution; −, no progeny; NA, not applicable.

  • b ND, not done.