TABLE 1.

Partial list of experimental systems for studying HDV genome replication

Strategy for initiation of HDV genome replicationSpecies and tissue or cells or cell linesReference
InfectionHuman liver34
Chimpanzee liver8
Woodchuck liver32
Mouse liver28
Chimpanzee-cultured hepatocytes39
Woodchuck-cultured hepatocytes41
DNA transfectionChimpanzee liver40
Woodchuck liver33
Mouse liver6
Mouse skeletal muscle30
Variety of cultured cell lines20
RNA transfectionMouse liver6
Variety of cultured cell lines25