Adjuvant effect of the adenoviral recombinantsa

Source of cytokineAmt of IFN (U)
Without XMG1With XMG1
Splenocytes + Adhu5rab.gp22
Splenocytes + AdC68rab.gp1212
Splenocytes without virus≤0.5
Recombinant mouse IFN-γ10248
  • a Splenocytes from naïve C3H/He mice were cultured with 10 PFU of the adenoviral recombinants per cell. Cell-free supernatants were tested for IFN without and with addition of the XMG1 antibody to IFN-γ. A recombinant IFN-γ was tested in parallel.