TABLE 4.

Genotypic properties of HIV-1 strains mutated at glycosylation sites in gp120

N-glycan positionResult for HIV-1(IIIB) isolatea:
123456789101112131415161718
88+/−+/−+++++++/−++/−
136
141
156
160++
186+
197
230+/−+/−+/−++/−+/−+/−+++++/−++
234+/−+/−+/−+/−+++++++++++
241
262
276+/−+/−
289+++++/−++++/−++/−
295+/−++++/−++/−++
301+/−++++++++++
332+/−++++++++/−++
339++++++++/−+++
356
386+
392+++/−++++/−++
397
406+++
448++/−+/−+++
463
  • a 1, PRMA-8-1; 2, PRMA-30-1; 3, PRMA-8-2; 4, PRMA-30-2; 5, PRMA-30-3; 6, PRMA-30-4; 7, UDA-20; 8, UDA-25-1; 9, UDA-50-1; 10, UDA-15-2; 11, UDA-50-2; 12, UDA-100-2; 13, UDA-200-2; 14, GNA-2.1; 15, HHA-2.2; 16, HHA-500CS; 17, HHA-500SN; 18, GNA-500CS; +/−, mixture of wild-type and mutant virus at the indicated amino acid position; +, deletion of an N-glycan at the indicated amino acid position.