TABLE 3.

Affinity constants of three anti-WNV antibodies as determined by SPR

Antibodykon (ka1; M−1 s−1)koff (kd1; s−1)KD (nM)
CR43742.34 × 104 ± 0.04 × 1041.30 × 10−3 ± 0.05 × 10−356 ± 4
CR43532.07 × 105 ± 0.05 × 1051.33 × 10−3 ± 0.04 × 10−36.5 ± 0.4
CR42831.23 × 106 ± 0.43 × 1068.26 × 10−4 ± 3.74 × 10−40.8 ± 0.6