TABLE 1.

Gross pathology and flow cytometry results of the leukemic micea

Mouse strainViral variantMorphotypeNo. of miceNo. of cases of indicated type of leukemia detected by flow cytometry:
AnemiaThymomaSwollen lymph nodesGlobalTBMEMk
BALB/cGV-1.21010L1010
+10NL+L11
    Total1191%9%
NFSGV-1.256L95 (3TM)4
+00NL33
+31NL+L33 (TE)
00NL+L211
    Total1748%29%23%
FVB/nGV-1.232L33 (1TM)
+00NL88 (2EMk)
+32NL+L31 (TE)2 (2ET)
    Total1428%72%
BALB/cGV-1.4108L1183 (1BM)
00NL+L21 (BM)1
+21NL+L21 (TB)1
    Total1464%28%8%
NFSGV-1.454L523
+00NL12363
+23NL+L31 (E)2
    Total2010%20%25%30%15%
FVB/nGV-1.433L33
+00NL219 (3EMk)12
+01NL+L11 (BM)
    Total2512%4%36%48%
  • a Abbreviations: L, lymphoid; NL, nonlymphoid; T, T cell; B, B cell; M, myeloid; E, erythroid; Mk, megakaryocytic. Parentheses indicate mixed or biphenotypic leukemias.