TABLE 2.

Dominant sequences in Gag in the five controllers

MacaqueWkSampleAmino acid change(s) in Gaga
V55Plasma viral RNAL216S
58Plasma viral RNAL216S, D244E, I247L, A312V, A373T
V35Plasma viral RNAL216S
64Plasma viral RNA(V145A), (P172S), L216S, D244E, (V375A), (P376S)
V45Plasma viral RNAL216S
12PBMC proviral DNAL216S
85PBMC proviral DNAL216S
V65Plasma viral RNAI377T
12PBMC proviral DNANo mutation
100PBMC proviral DNANo mutation
V85Plasma viral RNAQ58K
12PBMC proviral DNANo mutation
100PBMC proviral DNANo mutation
  • a Fragments containing the SIV gag region were amplified by nested RT-PCR and subjected to sequencing. Dominant mutations leading to amino acid changes are shown. The parentheses indicate that both the wild-type and the mutant sequences were detected clearly at the position.