TABLE 1.

Characteristics of Nef amino acids 160 to 165 among HIV-1 group M isolates

ParameteraPosition
160161162163164165
Residue in NL4-3 NefENTSLL
Residue in consensus NefENNCLL
% NP0.40.21.51.7100.0 (99.5 L)99.8 (99.5 L)
% UP0.389.0 (87.2 N)97.4 (92.0 N, 2.7 S, 2.6 T)94.9 (51.7 C, 41.1 S)0.00.2
% PC0.21.20.83.50.00.0
% NC99.1 (97.7 E, 1.3 D)9.6 (9.5 D)0.30.00.00.0
  • a NP, nonpolar (G, A, V, L, I, P, F, W, M); UP, uncharged, polar (S, T, C, Y, N, Q); PC, positively charged (K, R, H); NC, negatively charged (D, E).