TABLE 1.

Quantitation of the effect of phosphonacetic acid treatment on apoptosis in VZV-infected neurons measured by annexin V staining

Neuron typeaAnnexin V-positive neurons ± SEM (%)b
D1 p.i.D2 p.i.D4 p.i.
VZVVZV + PAAVZVVZV + PAAVZVVZV + PAA
Positive37.5 ± 1.735.5 ± 0.842.6 ± 2.340.3 ± 4.747.3 ± 5.844.6 ± 6.4
Test2.0 ± 0.72.0 ± 0.55.0 ± 1.76.6 ± 1.87.6 ± 2.48.6 ± 1.8
  • a Positive, positive control (5% ethanol-treated) neurons; test, neurons in VZV-infected culture.

  • b VZV indicates infection with VZV; VZV + PAA indicates infection with VZV plus treatment with PAA.