TABLE 1.

Comparison of yields of Ad5 in HeLa cells and HFFs

Multiplicitya of infectionYield, PFU/cellbYield ratioc
HFFHeLa
0.11.7140.12
10.036.7322.20.11
50.0125.0319.40.39
  • a Based on titer determined by plaque assay with HeLa cells.

  • b Yields were determined by duplicate plaque assays with HeLa cells. For clarity, standard deviations (± 15%) are not shown.

  • c Ratio of yield for HFFs to that for HeLa cells.