TABLE 3.

Cross-reactivity of anti-A/Vietnam/1203/04 (H5N1) HA MAbs with H5N1 viruses

HA phylogenyVirusReactivity with MAba:
VN04-2VN04-8VN04-9VN04-10VN04-13VN04-15VN04-16
Clade 1A/Vietnam/1194/04−10000−10
A/Hong Kong/213/030+1<0−2+1+1
Clade 2A, subclade 1A/Chicken/Indonesia/PA/03−3+1<0−200
A/Chicken/Malang/BBVet-IV/04−1+1<0−200
A/Chicken/Jogjakarta/BBVet-IX/04<<<0−1<−2
Clade 2E, subclade 2A/Whooper swan/Mongolia/244/05<0<0−20−2
Clade 2F, subclade 3A/Duck/Laos/3295/06<<−30<<−3
  • a Designations are the same as in Table 1. Values are the differences in log2 units between the HI titers of MAbs in the reactions with the A/Vietnam/1203/04 virus and with the other H5N1 viruses.