TABLE 1.

Summary of genetic analysis of VZV ORF0 to ORF4

ORFLocationSize (bp)Gene productHSV-1 orthologueMutant growth property
In vitroSCID-huRescue
0173-562390Putative transmembrane proteinUL56SlowSlowNormal
1589-915a327Putative transmembrane proteinNoneNormalNormalN/Ab
21134-1850717UnknownNoneNormalNormalN/A
31908-2447a540UnknownUL55NormalNormalN/A
42783-4141a1,359Posttranscriptional regulatorUL54EssentialN/ANormal
  • a Encoded on the bottom strand.

  • b N/A, not applicable.