TABLE 7.

mRNAs highly enriched in VLPsa

Affymetrix Probe IDMLV VLP signalCell signalFold change in MLV VLPsHIV VLP signalCell signalFold change in HIV VLPsGene
220028_at32727.1946.641.0710542.4791.213.74ACVR2B
211383_s_at25297.2582.639.675192.95037.73WDR37
212818_s_at19777.8666.539.126538.2684.211.24ASB1
226572_at17353.4460.834.783339.7521.36.96SOCS7
204181_s_at20751.4624.132.673156.9521.46.73ZBTB43
218496_at33111.5993.231.787356.81061.36.73RNASEH1
230085_at15230.1451.631.562573.1535.15.90PCYT1B
214004_s_at18659514.631.345298.1471.59.58VGLL4
224611_s_at19328.9917.729.862826.1593.14.32DNAJC5
201411_s_at19528.9477.728.256034898.89.19PLEKHB2
200738_s_at264214815−5.4408914252−3.58PGK1
  • a Data obtained for the MLV sample were used to select genes that were enriched compared to their cellular expression level. Very rare mRNAs were eliminated from consideration by removing probe sets with cell signals of <450. The corresponding fold changes in the HIV-1 samples are also shown. ASB1, PLEKHB2, and PGK1 were selected for further analysis by real-time RT-PCR.