Env fusion protein | Fusion/CSE ratio^{a} |
---|---|

F | 1.0 |

−T1 | 0.1 |

−T2 | 0.5 |

−T3 | 1.3 |

−T4 | 1.0 |

−T12 | 0.1 |

−T234 | 3.2 |

K1A | 5.5 |

K2A | 0.2 |

R3A | 0.3 |

N4A | 0.9 |

T5A | 0.9 |

↵

*a*The ratio of the normalized fusion and CSE values for each mutant was calculated from the data in Fig. 1D and 2C. By definition, the fusion/CSE ratio for WT NiV-F would be 1.0 (100%/100%). Ratios of >1 indicate increased fusogenicity, while mutants with decreased fusogenicity would have ratios of <1.