TABLE 1.

Fusion/CSE ratios

Env fusion proteinFusion/CSE ratioa
F1.0
−T10.1
−T20.5
−T31.3
−T41.0
−T120.1
−T2343.2
K1A5.5
K2A0.2
R3A0.3
N4A0.9
T5A0.9
  • a The ratio of the normalized fusion and CSE values for each mutant was calculated from the data in Fig. 1D and 2C. By definition, the fusion/CSE ratio for WT NiV-F would be 1.0 (100%/100%). Ratios of >1 indicate increased fusogenicity, while mutants with decreased fusogenicity would have ratios of <1.