TABLE 1.

Classification of human adenoviruses

SubgroupSerotypeTropism
A12b, 18, 31b
B13c,e 7, 16c, 21c, 50cRespiratory
B211c, 14c, 34, 35cRenal
C1, 2b,f, 5b,f, 6Respiratory
D8d, 9, 10, 13, 15b, 17, 19pb, 19ad, 20, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 33, 36, 37c,d, 38, 39, 42, 43, 44, 45, 46, 47, 48, 49, 51Ocular and other
E4bRespiratory
F40, 41bIntestinal
  • a Those viruses for which specific receptors have been identified are marked with footnotes; attachment or infection by these viruses has been demonstrated to depend on expression of the indicated receptors. Based on more limited experimental evidence, putative receptors can be assigned for several other serotypes, as discussed in the text.

  • b CAR.

  • c CD46.

  • d SA.

  • e CD80/86.

  • f Heparan sulfate.