TABLE 2.

Neutralization by anti-gp 120 RhMAbs

MAbConcn of MAb (μg/ml) reducing infectivity by 50%a
SIVmac239SIV239 E767StopSIV239-M5SIV239-M5 E767StopSIV316SIV316 E767Stop
3.11E2.84.80.004
1.9C0.008
1.10A12.50.0009
  • a The numbers indicate the concentration of MAb required to reduce infectivity of the indicated virus by 50%. —, 50% neutralization was not achieved at the highest concentration tested (11.75 μg/ml for 3.11E, 6.38 μg/ml for 1.9C, and 15 μg/ml for 1.10A).