TABLE 2.

Virological, clinical, and epidemiological features of SARS-CoV groupsa

GroupOriginDetection in phases of 2003 epidemicSpike gene analysis resultHuman infectionClinical featuresEpidemiological features
EarlyMiddleLateNo. of SNVs mutatedFormation of distinct phylogenetic group(s)Clinical presentationClose contact infectionContact history with patientContact history with animal(s)Responsible for large outbreak
PrototypePalm civet, raccoon dogNANANANoneYesNoNANANANANA
Low pathogenicityPalm civet, patientNANANA2-7YesYesMildNone identifiedNoYesNo
High pathogenicityPatientYesNoNo17-22YesYesSevereYesYesYesNo
EpidemicPatientNoYesYes25-27YesYesSevereYesYesNoYes
  • a NA, not applicable.