TABLE 1.

Putative phosphorylation sites for the N protein of SARS-CoV

EnzymeRecognition sequenceaPredicted positionbPatternc
CDK RGNSPAR 204-210 . . .([ST])P.[KR]
CK2 TGPE 116-119 ([ST]). .E
SAAE 251-254
GSK3SNQRS8-12([ST]). . .S
SRGGS177-181
SQASS181-185
SSRSS184-188
SRSSS185-189
SSSRS187-191
SRGNS191-195
STPGS198-202
TPGSS199-203
SRGNS203-207
PKARIT15-17R.([ST])
RAT90-92
RSS186-188
RNS196-198
PKBRSRGNSR190-196R.R. .([ST]).
PLKEASL119-122[DE].[ST][ILFWMVA]
CK1SWFT52-55S. .([ST])
SQAS181-184
SSRS184-187
SRSS185-188
SSRS188-191
SRNS195-198
SKVS233-236
MAPKAEVSPRW103-109. . .([ST])P. .
ALNTPKD139-145
RNSTPGS196-202
MEVTPSG323-329
  • a Respective amino acid sequence of N protein responsible for recognition by the corresponding enzyme.

  • b Number of amino acids from the N terminus.

  • c Putative consensus amino acid sequence required for recognition by the respective enzyme. [ ], either/or substitution; ( ), possible presence of both amino acid residues.