TABLE 3.

Virus titers in organs of mice infected with HK213Egg or HK213CK virusa

Virus and days p.i.Virus titer (mean log10 EID50 ± SD/g)
Nasal turbinatesLungsSpleenKidneysHeartBrainPancreasColon
HK213Egg
    12.2 ± 0.046.3 ± 0.2b1.72.0
    33.9 ± 0.57.8 ± 0.42.6, 3.51.9 ± 0.52.6 ± 0.62.6, 3.1
    64.4 ± 1.07.6 ± 0.41.6, 1.61.71.9, 2.1
HK213CK
    14.3 ± 0.02
    31.6, 2.56.8 ± 0.41.52.8
    66.5 ± 0.32.0
  • a BALB/c mice, anesthetized with isoflurane, were inoculated intranasally with virus (7 × 102 PFU/50 μl). Three animals from each infected group were euthanized on day 1, 3, or 6 p.i. for virus titration. When virus was not recovered from all three mice, individual titers were recorded.

  • b —, Virus was not isolated.