TABLE 3.

Integration in repeated sequencesa

Chromosomal featureFrequency (%) of repeated sequences at integration sites in:
Human genome (random sites)Stably expressed sites, HIV/JurkatInducible sites, HIV/JurkatHIV/SupT1HIV/PBMC
SINES
    Alu9.49.1 (0.8325)9.5 (0.9002)17.6 (<0.0001)10.1 (0.5246)
    MIR2.53.0 (0.4186)1.7 (0.3087)1.5 (0.107)3.2 (0.2713)
DNA elements2.72.1 (0.3491)3.9 (0.1207)2.4 (0.6898)3.9 (0.0844)
LTR elements (HERV)7.75.1 (0.0124)3.5 (0.0007)4.5 (0.0035)2.5 (<0.0001)
LINE18.021.2 (0.0368)15.2 (0.1207)19.2 (0.4347)15.5 (0.132)
Alpha satellite0.30.1 (0.5807)4.3 (<0.0001)0.5 (0.2987)0.0 (0.2142)
  • a The percentages are relative to all sites in the data set; values in parentheses are P values (chi-square) compared to random sites.