TABLE 1.

Productivity of Ad5 vectors carrying different deletionsa

DeletionTransgeneInsert size (kb)Yield (vp/cell)
E1-E3EGFP1.81.0 × 104
E1-E2-E3EGFP1.85.9 × 103
E1-E2-E3-E4orf3+EGFP1.85.0 × 103
E1-E2-E3-E4orf3+HCV10.54.9 × 103
  • a Titers were evaluated by real-time PCR on CsCl-purified vector stocks.