TABLE 2.

Comparison of amino acid sequences encoded by gene segments of representative lethal and nonlethal H5N1/04 influenza viruses

GeneAmino acid positionaVirusb
A/Vietnam/ 1203/04A/chicken/ Vietnam/ C58/04A/quail/ Vietnam/ 36/04
PB13VAV
328NKN
375NSN
PB2368RQR
391QEE
430PPT
447QHQ
627KEE
PA142EKK
151TIT
421ISS
595MLM
HA3KRK
52 (36)KTT
191 (175)LLM
250 (234)KRK
292 (276)TAT
544AVA
NP331MLM
NA26IIV
38ITI
46SAA
180NSN
264NDD
309NDN
M
M1
M261RRI
65TMT
NS
NS171GEE
89TNT
101MIM
132IIT
148EEG
200NSS
202DND
216*KK
226**
NS2/NEP48TAA
115AAT
  • a Numbering is based on the deduced amino acid sequence; numbers in parentheses refer to the numbering of the three-dimensional structure of A/duck/Singapore/97 (H5N1) (12).

  • b *, stop codon.