TABLE 2.

Comparison of putative CNGV-derived peptides by using Blastx

Clone (accession no.)FamilyGenusProteinAccession no.Identity (no. of amino acids with identity/total no. of amino acids [%])Conservation (no. of conserved amino acids/total no. of amino acids [%])Gaps (no. of gaps/total no. of amino acids [%])
A (AY208988)HerpesviridaeIctalurid herpesvirus 1Hypothetical protein ORF56NP04114737/138 (26)57/138 (41)
B (AY208989)BaculoviridaeSpodoptera littoralis nucleopolyhedrovirusRibonucleotide reductaseCAA6742374/163 (45)102/163 (62)
PoxviridaeMonkeypox virus14LNP53649274/162 (45)101/162 (62)
PoxviridaeVariola virusRibonucleoside-diphosphate reductase large chainNP04210274/162 (45)99/162 (61)
PoxviridaeEctromelia virusEVM057NP67157573/162 (45)99/162 (61)
BaculoviridaeEcotropis obliqua nucleopolyhedrovirusRibonucleotide reductaseAAQ8817564/123 (52)90/123 (73)
PoxviridaeVaccinia virus (strain WR)Ribonucleoside-diphosphate reductase large chainWZVZH473/162 (45)98/162 (60)
PoxviridaeCamelpox virusRibonucleotide reductase large subunitNP57046173/162 (45)98/162 (60)
NimaviridaeShrimp white spot syndrome virusRibonucleotide reductase large subunitAAK6935964/181 (35)98/181 (54)18/181 (9)
AsfarviridaeAfrican swine fever virus (strain Malawi)Ribonucleoside-diphosphate reductase large chainP2668545/109 (41)69/109 (63)
IridoviridaeInvertebrate iridescent virus 6Ribonucleoside-diphosphate reductase large chainNP14954848/113 (42)75/113 (66)4/113 (3)
HerpesviridaeEquine herpesvirus 1aRibonucleoside-diphosphate reductase large chainNP04103038/70 (54)51/70 (72)1/70 (1)
C (AY208990)PoxviridaeCowpox virusCPXV083NP619870124/190 (65)151/190 (79)
PoxviridaeCamelpox virusRibonucleotide reductase large subunitNP570461126/190 (66)151/190 (79)
PoxviridaeVariola virusRibonucleoside diphosphate reductase large chainNP042102123/190 (64)150/190 (78)
PoxviridaeVaccinia virus (strain WR)Ribonucleosite reductase large subunitP12848124/190 (65)149/190 (78)
NimaviridaeShrimp white spot syndrome virusLarge subunit of ribonucleotide reductaseNP477694104/193 (53)143/193 (74)1/193 (0)
AsfarviridaeAfrican swine fever virus (strain Malawi)Ribonucleoside-diphosphate reductase large chainP2668578/203 (38)107/203 (52)19/203 (9)
HerpesviridaeMeleagrid herpesvirus 1aUL39 ribonucleotide reductase large subunitNP07333362/168 (36)90/168 (53)1/168 (0)
D (AY208991)PoxviridaeYaba-like disease virus135R proteinNP07352024/74 (32)36/74 (48)2/74 (2)
HerpesviridaeHuman herpesvirus 8aK1 glycoproteinAAD2640317/66 (25)34/66 (51)
E (AY661550)PoxviridaeYaba monkey tumor virus135R protein serine protease inhibitorNP93833821/55 (38)30/55 (54)
PoxviridaeMyxoma virusM134R proteinNP05184819/56 (33)29/56 (51)
PoxviridaeSwinepox virusSPV131 VAR B22R homologueNP57029.119/56 (33)29/56 (51)
PoxviridaeLumpy skin disease virusLD131AAN02720.118/56 (32)32/56 (57)
PoxviridaeRabbit fibroma virusgp134RNP052023.119/56 (33)29/56 (51)
PoxviridaeSheeppox virusVARV B22R homologueNP659705.118/56 (32)35/56 (57)
PoxviridaeMolluscom contagiosum virusMCO35RNP043986.115/35 (42)23/35 (65)
PoxviridaeCowpox virusB7.5RAAB57929.117/55 (30)31/55 (56)
HerpesviridaeHuman herpesvirus 8ORF17 capsid assembly protein homologueAAB6267012/27 (44)16/27 (59)
  • a In general, similarity to Herpesviridae was not significant, but Herpesviridae is represented in the table as the most similar member of the family.