TABLE 4.

Class-specific residues present in the S and P domain surface patches for the P02 to P06 partitionsa

Partition and domainSurface patchClass-specific residuesNearest ACR(s)
P02170I, 201V*, 203A, 204G200F, 205R
    S domain2104V, 106N, 163E105G
344A**
    P domain CS-1 226Q* 225E
CS-2 414F*, 463D, 485P, 486N, 514K**, 519A 515P
CS-3 434P, 460H*, 500V 465D, 466T
CS-4 329H, 375W*, 377S
P05170I, 201V*, 203A, 204G200F, 205R
    S domain2104V, 106N, 163E, 174D, 178Q*105G
344A*
483L
    P domain CS-1 226Q*, 229R*, 227K* 225E
CS-2 414F*, 463D, 485P, 486N, 514K**, 519A, 520S** 515P
CS-3 434P, 460H*, 500V, 492P 465D, 466T
CS-4 329H, 375W*, 377S
P06170I, 192T*, 196T**, 199S*, 201V*, 203A, 204G200F, 205R
    S domain2103W, 104V, 106N, 163E, 174D, 178Q**, 183V, 94L105G
344A**, 46A, 218F42A, 105G
483L, 65Q, 82D*, 84S, 89L, 110R, 126S, 145F, 148V, 181R129P
    P domain CS-1 226Q*, 229R,* 227K* 225E
CS-2 414F*, 463D, 485P, 486N, 519A, 514K**, 520S* 515P
CS-3 434P, 460H*, 500V, 236L, 241L, 257P, 409I, 419V, 420F 465D, 466T
CS-4 329H, 375W*, 377S, 373L*
CS-5 306G, 310H
  • a These surface patches are subsets of all the surfaces shown in Table 2. The ACRs that occur nearest these surface patches are also shown. The P domain surface patches are shown in boldface. Accessible surfaces mostly consist of moderately and highly exposed residues that are shown with one and two asterisks, respectively.