TABLE 2.

Virus burdens in SCID/ICR mice after peripheral inoculation

VirusVirus burden (log PFU/g [± SEM])a in:
SerumbPeritoneumHeartLungMuscleSpleenLiverKidneyAdrenal glandsBrain
SPYF-MN3.2 (0.1)2.4 (0.3)1.1 (0.1)2.4 (0.3)2.0 (0.3)1.8 (0.4)0.62c0.50 (0.1)3.5 (0.4)8.5 (0.4)
SPYF-E3.3 (0.1)2.4 (0.1)1.5 (0.2)2.1 (0.2)2.5 (0.1)2.0 (0.3)0.95 (0.1)0.64c4.3 (0.3)8.0 (0.2)
SPYF-EIII2.7 (0.1)2.5 (0.1)1.2 (0.2)2.0 (0.2)2.7 (0.1)1.6 (0.0)0.65 (0.2)0.40c4.2 (0.1)7.6 (0.2)
SPYF-EI-II2.5c1.6 (0.9)1.0d2.1 (0.7)2.9 (0.3)3.0c0.91 (0.4)0.67d5.3 (0.5)7.5 (0.2)
  • a Data are titers based on groups of three to six mice, except as noted. Tissues were harvested at the time that individual mice exhibited signs of encephalitis.

  • b Data for serum are given as PFU per milliliter.

  • c n = 2.

  • d n = 1.