TABLE 1.

Frequency of detection in the MLN of RRV and SA11-Cl4 reassortant viruses following the oral inoculation of neonatal mice

VirusnaMLN growthbMLN titercParental origin of genome segmentd (gene product)
1 (VP1)2 (VP2)3 (VP3)4 (VP4)5 (NSP1)6 (VP6)7 (NSP3)8 (NSP2)9 (VP7)10 (NSP4)11 (NSP5)
RRV17100%2.8RRRRRRRRRRR
SA11-Cl4170%0.0SSSSSSSSSSS
R71080%3.7SSSSSSRSSSS
S1, 2, 3, 5, 71777%3.1SSSRSRSRRRR
S71060%3.8RRRRRRSRRRR
S4, 5, 7, 91855%3.3RRRSSRSRSRR
R4, 6, 91729%1.2SSSRSRSSRSS
R91614%0.7SSSSSSSSRSS
R41812%0.9SSSRSSSSSSS
R8, 9170%0.0SSSSSSSRRSS
R10170%0.0SSSSSSSSSRS
R11180%0.0SSSSSSSSSSR
  • a n, the number of individual pups inoculated with each virus.

  • b MLN growth is measured as the percentage of animals in which virus was recovered from the MLN at 3 days postinoculation.

  • c Titers are the mean titers of the virus in virus-positive MLN at 3 days postinoculation.

  • d RRV-derived genome segment numbers have been converted to SA11 functional equivalents.