TABLE 1.

Characteristics of nef genes from NP, SP, and RP patientsa

Progression groupnef genesMean nef activity (SE)
Total no. analyzed% CD4 downregulation activity% MHC-I downregulation activityCD4 downregulationMHC-I downregulation
<2525-75>75<2525-75>75
NP81256502864764.4 (5.0)63.0 (5.2)
SP372134223391.4 (4.0)92.5 (4.2)
RP64127451005480.8 (5.4)90.3 (4.8)
  • a Grossly defective nef genes are included.