TABLE 1.

Patient characteristics

Patient no.Allele(s) for HLA class IYr of diagnosisSample dateNo. (cells/μl) of:Viral load (copies/ml)SourceQW9 5th aaa
ABCCD4+ T cellsCD8+ T cells
LTNPs
    52, 24576, 719859/99971870<50Proviral DNAE
    71, 257619858/98371551<50Proviral DNAE
    923, 2657, 441, 719973/991,079985<50Proviral DNAE
    123, 1157, 76, 719863/01500218<50Proviral DNA D
    131, 1157, 354, 619864/991,016767<50Proviral DNAE
    341, 257, 86, 719893/011,5231,111<50Proviral DNAE
    3031, 7457, 517, 16199011/0045082856Proviral DNAE
    611, 3057, 527, 1219866/99737998152Virion RNAE
    811, 2357, 444, 619855/004901,033567Virion RNAE
    253, 2457, 272, 619864/005417271,089Virion RNAE
Untreated     progressors
    352, 3576, 720008/006366181,149Virion RNAE
    20330, 3257, 188, 1419891/971,3601,1708,255Virion RNA D
    1063, 3057, 185, 1819867/005461,95924,245Virion RNA D
    1192, 2557, 444, 619853/985121,63824,640Virion RNAE
    1052, 8057, 82, 7199210/9633386625,040Virion RNA D
    1436, 6857, 457, 1619987/9830683826,260Virion RNAE
    107357, 403, 719877/005301,51926,740Virion RNA D
    1231, 1157, 553, 619926/9318985252,960Virion RNAE
    11036, 6857, 457, 1619856/9822670463,480Virion RNAE
    1011, 3157, 516, 15198611/9426058891,910Virion RNAE/D
    114257, 516, 1419895/98317382156,700Virion RNAE
    10224, 6857, 156, 7199311/95624798183,000Virion RNAE
Treated     progressors
    11632, 6857719938/961,4331,5381,200Virion RNAE
    1152, 2557, 444, 619958/963934371,245Virion RNA D/E
    1032, 1157, 553, 619916/984636782,249Virion RNA D/E
    104257, 583, 619883/982911,0283,507Virion RNA D
    1221, 257, 516, 14198612/965959845,371Virion RNAE
  • a Amino acids (aa) in boldface indicate the E312D variation. E/D, admixture of consensus sequence and the E312D variation.