TABLE 1.

Comparison of the genomic organizations of the UK BoCVs sequenced in the present study, the German Bo/Jena/80/DE, and human genogroup I and II NLVs, as predicted by the NCBI ORF finderk

VirusORF1-2 overlap (nt)ORF2 capsid length (aa)Capsid MW (kDa)ORF2-3 overlap (nt)ORF3 length (aa)3′ NTR length (nt)
BoCVs
    Newbury2/76/UK1452256.920928243
    Dumfries/94/UK1452256.720928243
    Aberystwyth24/00/UK1452257.020928243
    Penrith55/00/UK1452257.020928243
    Jena/80/DE14a519a56.6a11a223a70a
Human NLVs
    Genogroup I17b530-547c56.6-58.8d1b210-223e66-91e
    Genogroup II20-35f535-550g58.7-60.0h1f252-268i45-85j
  • a From reference 28.

  • b Based on data for Hu/NLV/Norwalk/68/US (22), Hu/NLV/Chiba/87/JP (42), Hu/NLV/Seto/124/89/JP (23), Hu/NLV/Desert Shield/90/SA (25), and Hu/NLV/Southampton/91/UK (24).

  • c Based on data for Hu/NLV/Norwalk/68/US (22), Hu/NLV/Chiba/87/JP (42), Hu/NLV/Desert Shield/90/SA (25), Hu/NLV/Hesse3/97/DE (39), Hu/NLV/Southampton/91/UK (24), Hu/NLV/Musgrove/89/UK, Hu/NLV/Thistlehall/90/UK, Hu/NLV/Birmingham/93/UK, Hu/NLV/Winchester/94/UK, Hu/NLV/Valetta/95/Malta, Hu/NLV/Sindlesham/95/UK, and Hu/NLV/Whiterose/96/UK (11).

  • d Based on data for Hu/NLV/Norwalk/68/US (22), Hu/NLV/Chiba/87/JP (42), Hu/NLV/Desert Shield/90/SA (25), and Hu/NLV/Southampton/91/UK (24).

  • e Based on data for Hu/NLV/Norwalk/68/US (22), Hu/NLV/Chiba/87/JP (42), and Hu/NLV/Southampton/91/UK (24).

  • f Based on data for Hu/NLV/Hawaii/71/US (26), Hu/NLV/Melksham/89/UK (14), Hu/NLV/Mexico/89/MX (21), Hu/NLV/Toronto/24/91/CAN (27), Hu/NLV/Lordsdale/93/UK (8), Hu/NLV/Camberwell/94/AUS (5), and Hu/NLV/Mendoza/320/95/ARG (20).

  • g Based on data for Hu/NLV/Hawaii/71/US (26), Hu/NLV/Snow Mountain/76/US (19), Hu/NLV/Melksham/89/UK (14), Hu/NLV/Mexico/89/MX (21), viruses Hu/NLV/Hillingdon/90/UK, HU/NLV/Leeds/90/UK, Hu/NLV/Seacroft/90/UK, Hu/NLV/Girlington/93/UK, Hu/NLV/Bham132/95/UK, Hu/NLV/Parkroyal/95/UK, Hu/NLV/Symgreen/95/UK, Hu/NLV/Rbh/93/UK, and Hu/NLV/Wortley/90/UK (11), Hu/NLV/Toronto 24/91/CAN (27), Hu/NLV/Lordsdale/93/UK (8), Hu/NLV/Camberwell/94/AUS (5), Hu/NLV/Grimsby/95/UK (17), Hu/NLV/Mendoza320/95/ARG (20), and viruses Hu/NLV/Alphatron/98-2/98/NET and Hu/NLV/Amsterdam/98-18/98/NET (47).

  • h Based on data for Hu/NLV/Hawaii/71/US (26), Hu/NLV/Snow Mountain/76/US (19), Hu/NLV/Melksham/89/UK (14), Hu/NLV/Mexico/89/MX (21), Hu/NLV/Toronto24/91/CAN (27), Hu/NLV/Lordsdale/93/UK (8), Hu/NLV/Camberwell/94/AUS (5), Hu/NLV/Grimsby/95/UK (17), and Hu/NLV/Mendoza320/95/ARG (20).

  • i Based on data for Hu/NLV/Melksham/89/UK (14), Hu/NLV/Lordsdale/93/UK (8), Hu/NLV/Camberwell/94/AUS (5), and Hu/NLV/Mendoza320/95/ARG (20).

  • j Based on data for Hu/NLV/Melksham/89/UK (14), and Hu/NLV/Lordsdale/93/UK (8).

  • k nt, nucleotide; aa, amino acid; NTR, nontranslated region.